Continuing where left off, Jesse now possessed by Genesis—the unholy offspring of an angel and demon—holds Word of God, an ability to command anyone or anything with a mere utterance. And he'll use this power to hold the Lord accountable for the people He has forsaken. From the ashes of a small-town church to the bright lights of New York City to the backwoods of Louisiana, Jesse Custer cuts a righteous path across the soul of America in his quest for the divine—an effort that will be met by every evil that Heaven and Earth can assemble. Joined by his gun-toting girlfriend, Tulip, and the hard-drinking Irish vampire Cassidy, Jesse will stop at nothing to fulfill his quest to find God.