At its onset, the American Indian Women of Proud Nations Organization set out to create a space that would uplift Native American women, children, and families because of their central roles in the continuation of Native communities. The contributors to the second edition continue to document and reflect on the organization’s initiative and the efforts of Southeastern Native women and their allies to center women, children and families in protecting and strengthening kinship, land, and language as enduring aspects of Native American cultures. The second edition offers updated research on language revitalization, adolescents and their parental caregivers, Indigenous issues in higher education, and new work on matrilineality, the Missing and Murdered People crisis, and the continuation of healing traditions in a contemporary context.