This United States Army manual, Army Regulation AR 380-5 Army Information Security Program March 2022, develops Department of the Army (DA) policy for the classification, downgrading, declassification, transmission, transportation, and safeguarding of information requiring protection in the interests of national security. It primarily pertains to classified national security information, or classified information, but also addresses Controlled Unclassified Information (CUI). For purposes of this regulation, classified national security information, or classified information, is defined as information and/or material that has been determined, pursuant to Executive Order (EO) 13526, or any applicable predecessor order, to require protection against unauthorized disclosure and is marked to indicate its appropriate classification. This regulation implements EO 13526; EO 13556; DoDM 5200.01, Volumes 1 through 3; and DoDI 5200.48. This regulation also establishes policy on the safeguards of Restricted Data (RD) and Formerly Restricted Data (FRD), as specified by the Atomic Energy Act of 1954, as amended.