This thorough volume explores prools of proteome- and metabolome-wide strategies for the identification of protein-small molecule complexes in different organisms, in order to shed light on these important regulatory interactions. Experimental and computational strategies to characterize protein-metabolite interactions are discussed, and recent advances in enabling technologies are featured as well. Written for the highly successful
Methods in Molecular Biology
series, chapters include the kind of detail and expert implementation advice to ensure success in future research.
Authoritative and practical,
Cell-Wide Identification of Metabolite-Protein Interactions
will aid researchers seeking a better understanding of the mechanisms of signal transduction occurring in the cell and assessing the effect of complex formation on cell physiology.