This volume provides essential and fundamental prools on manipulation chromosome. Chapters details methods on the preparation of mitotic chromosome, chromosome aberration, micronucleus (MN), comet assay, karyotyping, Fluorescent
in situ
hybridization (FISH), premature chromosome condensation (PCC), immunohishemistry (IHC) staining, new generation sequencing technology and new chromosome concepts, such as epigenetic and its cause of cancer are presented. Written in the format of the highly successful
Methods in Molecular Biology
series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible prools.
Authoritative and cutting-edge,
Chromosome Analysis: Methods and Prools
aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.