Perhaps more than any other American city, Chicago has been a center for the study of both urban history and economic inequity. assembles a century of research to show the range of effects that Chicago’s structural socioeconomic inequalities have had on patients and medical facilities alike. The work collected here makes clear that when a city is sharply divided by power, wealth, and race, the citizens who most need high-quality health care and social services have the greatest difficulty accessing them. Achieving good health is not simply a matter of making the right choices as an individual, the research demonstrates: it’s the product of large-scale political and economic forces. Understanding these forces, and what we can do to correct them, should be critical not only to doctors but to sociologists and students of the urban environment—and no city offers more inspiring examples for action to overcome social injustice in health than Chicago.