This photo book shows the pictures of the places of interest and other major tourist attractions in Santiago de Cuba, the second largest city in Cuba, and the home of Cuban Revolution. Brief information about Cuba and the history of Santiago de Cuba were also provided to help readers appreciate the context of the pictures. The pictures shown in the book were taken in 2006, about 9 years before the recent thawing of relations between Cuba and USA. Hence, it is hoped that it would provide a good visual representation of the conditions of the important and historic buildings and other places of interest, at the time the pictures were taken. The pictures includes that of notable places of interest in the city such as Cespedes Park, Diego Velasquez House, Cathedral of Santiago, Emilio Bacardi Museum, Revolution Square, Moncada Barracks, Santiago Bay and El Morro Fortress, Port of Santiago, The Cobre Sanctuary, parks and plazas, and of ordinary people on the street. The photo book is the second in the series of five volumes which are: Cuba in Pictures: Havana; Cuba in Pictures: Santiago de Cuba; Cuba in Pictures: Camagüey; Cuba in Pictures: Viñales & Varadero; and Cuba in Pictures: Cienfuegos, Trinidad & Guanayara.