Entomologist Frank Travis takes his family on a weeklong vacation to a remote resort in the Amazon jungle. Frank doesn't mind that the kids will be tagging along; he's more worried that they won't share his sense of adventure, especially how he is always bragging that everything is bigger in the Amazon. Words he will soon regret. After an earthquake, the family gets separated and must struggle to survive in a perilous region of the jungle never explored before. An unbelievable world filled with incredible creatures and impending danger, certainly not the vacation everyone had in mind.