This volume unites a diverse, international group of education scholars whose work exemplifies the affordances and constraints of the comparative case study (CCS) approach and offers new theoretical and empirical directions for researchers. In 11 engaging chapters, experts in comparative education, early childhood education, peace education, refugee education, special education, and teacher education discuss their use of the CCS approach to produce new ways of knowing and to address challenges of multi-scalar and multi-sited research. The first section, emphasizes the importance of carefully selecting cases during different phases of research while continuously reflecting on how these choices influence the findings. The second section, addresses the challenge of balancing the need for rich, deep data while including multiple sites. The third section, demonstrates the fit between the CCS approach and qualitative research that unfolds over time and space. , the fourth section, showcases research with a strong temporal dimension. The final section, , suggests inspiring and innovative methods. Offering rich methodological examples and provocative discussion questions, this volume will appeal to undergraduate and graduate students in education and research design courses, and to scholars and policymakers in diverse fields seeking to design studies of complex phenomena at different sites and scales.