A group of leading international scholars here discuss the central chapters of Paul's letter to the Romans. These trilingual essays are the fruits of the 25th Colloquium Oecumenicum Paulinum, which met in September 2018 at the Abbazia di San Paolo fuori le Mura. Tracing the language, structure, flow, and purpose of these seminal chapters, the authors here highlight Paul's radical analysis of the human condition, the power of grace, co-crucifixion with Christ, the agency of the Spirit, and the combination of lament and hope in the midst of suffering. Paul's slavery metaphor, his marriage analogy, and the purpose and reference of the famous statements of the "I" in Romans 7 are all here discussed in depth. What emerges throughout is Paul's consistent confidence in the love of God in Christ, and his assurance that God has re-directed the cosmos towards life, in the resurrection of Christ.