In this issue of Thoracic Surgery Clinics, guest editors Drs. Jonathan Yeung and Elena Elimova bring their considerable expertise to the topic of Esophageal Cancer. Nearly 20,000 new cases of esophageal cancer are diagnosed each year in the U.S. alone. In this issue, top experts provide a timely update of this perennially important topic with coverage of pathology, genetics, staging, adjuvant therapies, and surgical management, as well as two special articles on controversies in esophageal cancer.