The harmful use of alcohol creates a significant disease burden and in many countries causes public health problems leading to a substantial health, social and economic burden. Reducing the harmful use of alcohol is becoming a priority on the national, regional and global levels; it can be done by implementing strategies of proven effectiveness.This report presents the latest data from the WHO European Region on alcohol consumption and harm and the responses made to them in countries. It summarizes the situation in the Region as a whole and gives profiles of the 53 Member States, presenting consolidated tables and graphs with data on some of the key indicators from the 2009 survey on alcohol and health. In addition, the report describes the WHO instruments and activities that are available to support countries in building on the gains they have already made in this area.