The intensively discussed term transformation refers to the comprehensive restructuring of processes and behaviour in order to address societal challenges posed by far-reaching changes in energy, transport, production and agricultural systems. Since such complex transformations are always accompanied by uncertainties about their effects and consequences, the contributions in this volume critically examine the opportunities and risks involved in these processes and discuss the possibilities and limits of technology assessment in the context of societal transformations. The volume brings together the academic contributions to the 8th international conference of the Technology Assessment Network, which took place in Karlsruhe from 7th to 8th November 2018.