This handbook is a timely resource for the rapidly growing field of heavy-ion transport-model theory and its applications to the fields of accelerator development, heavy-ion radiotherapy, and shielding of accelerators and in space.Data from over 20 years of experiments in the production of secondary neutrons and spallation products are contained in the handbook, and are available on the accompanying CD. Transport modelers and experimentalists will find the detailed descriptions of the experiments and subsequent analyses to be a valuable aid in utilizing the data for their particular applications.