This volume discusses experimental brain injury models that contain valuable information carefully chosen to widen the researchers’ horizon about neurotrauma. Injury Models of Central Nervous System: Methods and Prools contains relevant experimental design approaches that have been adapted and made ready for application in laboratory settings. For easier navigation, the chapters are categorized into 6 parts: Introduction, General Consideration in Using Animal Laboratory in CNS Injury Research, Classical TBI Models and Their Link with Pathophysiological Features of CBS Injury – Models, Special Topics in CNS Trauma: Comorbid Conditions in CNS Injury, Outcome Measures in Brain Injury Models, and Future Directions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory prools, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, Injury Models of Central Nervous Systems: Methods and Prools, is a very useful reference towards the progress of this discipline.