Johnny Reno (Dana Andrews) is a US Marshall who is bushwhacked by outlaws on his way to Stone Junction, Kansas. Joe Connors (Tom Drake) and his brother Ab (Dale Van Sickle) mistakenly believe the lawman is after them and fire on Reno, and Reno captures Joe after Ab is killed in the gun battle. The two face an angry mob in a town where local Sheriff Hodges (Lon Chaney, Jr.) is in cahoots with the corrupt Mayor Jess Yates (Lyle Bettger). Although Reno believes Joe may have killed an innocent Indian, he must protect the prisoner from the growing mob that threatens to lynch the man before his trial. Jane Russell plays Johnny's sweetheart Nona, owner of the local saloon.