Sir William Osler, a legendary physician of an earlier era, once said, "Medicine is a science of uncertainty and an art of probability." In Osler’s day, and now, decisions about treatment often cannot wait until the diagnosis is certain. is about how to make the best possible decision given that uncertainty. The book shows how to tailor decisions under uncertainty to achieve the best outcome based on published evidence, features of a patient’s illness, and the patient’s preferences. describes a powerful framework for helping clinicians and their patients reach decisions that lead to outcomes that the patient prefers. That framework contains the key principles of patient-centered decision-making in clinical practice. Since the first edition of Medical Decision Making in 1988, the authors have focused on explaining key concepts and illustrating them with clinical examples. For the Third Edition, every chapter has been revised and updated. Written by four distinguished and highly qualified authors, includes information on: is a valuable resource for clinicians, medical trainees, and students of decision analysis who wish to fully understand and apply the principles of decision making to clinical practice.