During the twentieth century, medicine has been radically transformed and powerfully transformative. In 1900, western medicine was important to philanthropy and public health, but it was marginal to the state, the industrial economy and the welfare of most individuals. It is now central to these aspects of life. Our prospects seem increasingly dependent on the progress of bio-medical sciences and genetic technologies which promise to reshape future generations. The editors of have commissioned over forty authoritative essays, written by historical specialists but intended for general audiences. Some concentrate on the political economy of medicine and health as it changed from period to period and varied between countries, others focus on understandings of the body, and a third set of essays explores transformations in some of the theatres of medicine and the changing experiences of different categories of practitioners and patients.