Although efforts have been made and continue to be made to reduce the rate of HIV transmission in the U.S. and globally, the rates continue to increase in the majority of countries. In the U.S., members of minority communities remain especially at risk of HIV transmission. An individual’s discovery that he or she has contracted HIV, or that a loved one has contracted the illness, often raises significant issues that necessitate interaction with mental health professionals. Mental Health Practitioner’s Guide to HIV/AIDS serves as a quick desk reference for professionals who may be less familiar with the terminology used in HIV/AIDS care and services.