This volume examines the role of mihondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mihondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mihondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mihondria and other cellular components, including the important role of mihondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material.
Mihondria and Cell Death
, part of the
Cell Death in Biology and Diseases
series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology,as well as those interested in the study of mihondria and cell biology.