Mihondria: Practical Prools offers a broad collection of methods for studying the molecular biology, function, and features of mihondria. In the past decade, mihondrial research has elucidated the important influence of mihondrial processes on integral cell processes such as apoptosis and cellular aging. This practical guide presents a wide spectrum of mihondrial methods, each written by specialists with solid experience and intended for implementation by novice and expert researchers alike.
Part I introduces major experimental model systems and discusses their specific advantages and limitations for functional analysis of mihondria. The concise overview of general properties of mihondrial systems is supplemented by detailed prools for cultivation of model organisms. Parts II-VI comprise a robust collection of prools for studying different molecular aspects of mihondrial functions including: genetics and microbiology, biochemistry, physiology, dynamics and morphology, and functional genomics. Emphasis is placed on new and emerging topics in mihondrial study, such as the examination of apoptotic effects, fusion and fission of mihondria, and proteome and transcriptome analysis.