The monograph is devoted to the problem of morphofunctional features of the nuclear apparatus of liver hepatocytes in various regenerative processes. The authors have analyzed and summarized the world data of modern literature, performed in the field of pediatrics, hepatology, surgery having theoretical and practical importance. The monograph presents the results of own researches carried out by morphological and histochemical methods. The peer-reviewed work have prognostic value for the practical doctor pediatricians, hepatologists and surgeons, as well as students and masters of medical universities.