Max Stonecrop, venture capitalist, and Federica Ratzow, pre-med student and polyglot, meet on an overnight train to Venice and then re-connect seven years later when Stonecrop turns up as her patient at Universitätsspital, Zürich. As Stonecrop recovers from a climbing accident and a violent, traumatic experience in Mozambique, they grow close. Federica suddenly vanishes, prompting Stonecrop and Federica's criminal father to team up against Yakuza gangsters, corrupt business associates, and dangerous men from Federica's past.