This volume presents an assortment of traditional and emerging experimental procedures relevant to Schwann cell research. The chapters are divided into four parts. Part I contains prools for
in vitro
culture, purification, and characterization of primary Schwann cells from diverse species and stages of nerve development. It also contains prools to create cancer cell lines and engineered Schwann cells from unconventional sources via chemical conversion, induced differentiation or genetic intervention. Parts II and III outline a wide range of methodologies used to study Schwann cells within
and
in vivo
systems relevant to the analysis of peripheral nerve development, cancer, axon degeneration/regeneration, and myelination. Last but not least, part IV outlines prools for Schwann cell production, collection, labeling and transplantation in the injured peripheral nerve and spinal cord of experimental animals and human subjects.
Authoritative and practical,
Schwann Cells: Methods and Prools
aims to aid both experienced and new investigators to make progress in their research endeavors involving Schwann cells.