The prevalence of obesity is increasing day by day and is the epidemic of the 21st century. In a recent analysis by WHO, it was found that 1.9 billion people aged 18 years or more were overweight, out of which 600 million were obese. The world obesity population has doubled over the last two decades. Obesity is associated with many diseases. Some of them are diabetes, hypertension, hyperlipidemia, asthma, degenerative bone disease, obstructive sleep apnea, which cause debilitating problems in the obese and add to the cost of health care. Increased body mass index (BMI), abdominal fat and weight gain are important risk factors associated with the development of type II diabetes mellitus (T2DM). About 90% of people with T2DM are obese. Bariatric surgery is now a well-established procedure for treating morbid obesity and its associated comorbidities. Sleeve gastrectomy is becoming the most popular procedure to date owing to its technical simplicity and less malnutrition. This book reviews surgical techniques, clinical outcomes and potential complications of sleeve gastrectomy.