This book explores culture, development, and spirituality from the perspective of social work. This framework serves as foundation and guides analytical deliberation through the use of case studies from around the world. With emerging trends in development, synchronistic synthesis between the inner self and interventions, it is anticipated to contribute to advancing well-being of all people. The book reflects global experiences from both the social work professions and development practitioner’s perspectives, as it pertains to economic and social development. The book serves as a guide to those who want to better understand and incorporate spirituality into successful social work interventions, practice, and research. It examines social development in the daily lives of children and families by looking at larger national and international phenomenon that can affect the well-being of communities. The book further discusses natural disasters, poverty, war, migration, human trafficking, war, violence and other factors with suggestions of innovative global interventions that have been utilized to assist diverse marginalized groups and communities.