The object of this work is the interdisciplinary dialogue between natural sciences and Christian theology. The objective is to study the theological, epistemological and semantic conditions that make possible an articulation between scientific worldviews and theological discourses. In this study "to articulate" means that scientific theories and theological discourses do not share the same semantic horizon. At the same time, the verb "to articulate" implies that there is a possible mediation between scientific worldviews and systematic theology. The main thesis of this study is that an articulation between scientific worldviews and systematic theology is possible through the mediation of philosophy. Natural sciences and philosophy refer to the order of manifestation where real things appear as phenomena. Christian theology refers to the order of revelation where God communicates Himself to the human person. The relationship between these two orders can be expressed with the maxim: neither confusion nor separation. Furthermore, there is a positive formulation of that relation: revelation assumes and transfigures what is manifested. This model of relation is the fundamental theological condition that makes possible an articulation between natural sciences and theology. In addition, there is an epistemological condition: the homologous rational structure of each rational field (sciences, philosophy and theology). Based on these theological and epistemological conditions, this research work proposes a theological method that articulates scientific worldviews into systematic theology through the mediation of philosophy. The method seeks two objectives: (a) that theology remains in ist epistemological boundaries and (b) to respect symmetrically the autonomy of natural sciences' procedures. Finally, the proposed method is applied to three examples: the elaboration of theological discourses, in dialogue with natural sciences, about (i) creation, (ii) human action and (iii) a spiritual contemplation of God's presence in the world. This research follows the contributions of two major scholars of the twentieth century: Jean Ladriere and Xavier Zubiri. Our considerations are based on the scholars' analyses of the plurality of epistemologies and their analyses of the intellectual act.