Excerpt from The Etiology of Beri-Beri
Epidemically and endeniically the occurrence of beri-beri is certainly greatest in those tropical and subtropical countries whose inhabitants partake of a diet in which rice forms an important and generally the staple constituent. The other articles of diet \aiy with the country but rice varies merely in kind or quality and but little in regard to the quantity consumed.
In those countries where the disease is endemic the incidence has always been greatest among the poorer classes, inmates of p.1blic institutions and the like. Supporters of dietary hypotheses have therefore sought to account for the occurrence of the disease in that the diet consumed was deficient in some substance or substances essential for nutrition and those workers who have incrimiiiated rice consider either that a diet in which this article bulks largely is deficient in protein or fat, or that the rice has become diseased from the action of moulds or other organisms.
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