The Globalization of the U.S. Small Business Innovation Research (SBIR) Program presents how SBIR programs have spread across the globe. The U.S. SBIR program has become a template for legislation in other countries that seek to enhance the innovative nature of small firms. This special issue presents works by leading eminent scholars who describe individually the population of international emulated programs. The works are ordered by the date that the country adopted an SBIR-like program, including Turkey (1995), Australia (1996), Brazil (1997), South Korea (1998), Japan (1999), Taiwan (1999), United Kingdom (2001), The Netherlands (2004), and New Zealand (2012).