Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor microenvironment during cancer development. Furthermore, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include elastin, decorin, syndecan-1, versican, lipoproteins, brevican, thrombospondin, and much more. Taken alongside its companion volumes, updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newest generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book is an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapters authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.