This book is a bold, innovative examination of the factors behind the low representation of women in scientific disciplines and, more broadly, other competitive professional career tracks. A group of 25 women, from diverse backgrounds and representing a cross-section of points along the career continuum, provide a candid look at a scientific environment where women are routinely judged more by stereotype than ability and travel the road to success in isolation. The book provides strategies for negotiating through gender-specific boundaries and showcases two programs designed to support women in establishing successful scientific careers.